249736-14-9Relevant academic research and scientific papers
Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids
Dragovich, Peter S.,Webber, Stephen E.,Prins, Thomas J.,Zhou, Ru,Marakovits, Joseph T.,Tikhe, Jayashree G.,Fuhrman, Shella A.,Patick, Amy K.,Matthews, David A.,Ford, Clifford E.,Brown, Edward L.,Binford, Susan L.,Meador III, James W.,Ferre, Rose Ann,Worland, Stephen T.
, p. 2189 - 2194 (2007/10/03)
Tripeptide-derived molecules incorporating N-methyl amino acid residues and C-terminal Michael acceptor moieties were evaluated as irreversible inhibitors of the cysteine-containing human rhinovirus 3C protease (3CP). Such compounds displayed good 3CP inh
