249750-87-6Relevant academic research and scientific papers
A New Platinum Complex Catalyzed Reaction Involving Nucleophilic Substitution at the Central Carbon Atom of the π-Allyl Ligand
Kadota, Joji,Komori, Shinji,Fukumoto, Yoshiya,Murai, Shinji
, p. 7523 - 7527 (1999)
The reaction of 2-chloro-allyl acetate with sodium ethyl acetoacetate in the presence of a platinum-(0) complex gave furan derivatives. The key feature of this new platinum-catalyzed reaction is the nucleophilic substitution at the central carbon atom of π-allyl complexes. The regioselectivity of the nucleophilic attacks (central or terminal) is dependent on the pKa of the nucleophile. In addition, a labeling experiment revealed that a rapid syn-anti isomerization of the (π-allyl) platinum complexes occurs.
