249762-01-4 Usage
Chemical structure
Contains a piperidine ring, a tert-butoxycarbonyl (Boc) protecting group, and a carboxylic acid functional group.
Functional groups
Carboxylic acid, Boc protecting group, and piperidine ring.
Application
Used as a building block in organic synthesis, particularly in the pharmaceutical industry for the production of various drugs.
Selectivity
The presence of the Boc protecting group allows for selective manipulation of the piperidine ring.
Intermediate
A valuable intermediate in the synthesis of complex organic molecules.
2-Methyl substitution
May impart specific chemical and biological properties to the compound.
Importance in drug design
The 2-methyl substitution on the piperidine ring makes it a potentially important moiety in drug design and discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 249762-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,9,7,6 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 249762-01:
(8*2)+(7*4)+(6*9)+(5*7)+(4*6)+(3*2)+(2*0)+(1*1)=164
164 % 10 = 4
So 249762-01-4 is a valid CAS Registry Number.
249762-01-4Relevant articles and documents
Synthesis and in vitro characterization of new growth hormone secretagogues derived from ipamorelin with dipeptidomimetic N-terminals
Peschke, Bernd,Ankersen, Michael,Sehested Hansen, Birgit,Kruse Hansen, Thomas,Langeland Johansen, Nils,Lau, Jesper,Madsen, Kjeld,Petersen, Hans,Thogersen, Henning,Watson, Brett
, p. 363 - 380 (2007/10/03)
The structural requirements for N-terminal features for the minimal structure of growth hormone secretagogues derived from ipamorelin are investigated. It is found, that incorporation of nonpolar peptidomimetic amino acids at the N-terminal can replace the Aib-His moiety and lead to compounds with high in vitro potency with respect to their growth hormone secretagogue properties. New unnatural amino acids with double bonds, ether- linkages, and 1,3-phenylene-moieties in the backbone proved to be valuable dipeptidomimetics. Using them, growth hormone secretagogues with high potencies were obtained.
