2499-68-5

Basic information

• Product Name: 4-Iod-3-nitrobiphenyl
• Synonyms: 4-Iod-3-nitrobiphenyl
• CAS NO: 2499-68-5
• Molecular Weight: 325.106
• Mol File: 2499-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Iod-3-nitrobiphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iod-3-nitrobiphenyl(2499-68-5)
• EPA Substance Registry System: 4-Iod-3-nitrobiphenyl(2499-68-5)

Safety Data

• Hazardous Substances Data: 2499-68-5(Hazardous Substances Data)

Upstream product

• 20691-72-9 4-iodo-2-nitroaniline 
• 98-80-6 phenylboronic acid 

Downstream Products

• 960307-40-8 C₂₇H₂₅N₃O₅ 
• 960307-25-9 C₂₇H₂₅N₃O₃ 
• 2499-76-5 2'',3'-Diamino-p-quaterphenyl 
• 2499-69-6 2'',3'-dinitro-p-quaterphenyl 

Relevant articles and documents

TARGETING THE ONCOPROTEIN NUCLEOPHOSMIN

(+)-Avrainvillamide, a naturally occurring alkaloid with antiproliferative activity, is shown to bind to the oncoprotein nucleophosmin. Nucleophosmin is known to regulate the tumor suppressor protein p53 and is overexpressed in many different human tumors. The invention provides methods of modulating nucleophosmin and p53 using (+)-avrainvillamide and analogues thereof. These compounds may provide leads for the development of novel anti-cancer therapies that target nucleophosmin.