24992-04-9Relevant articles and documents
Synthesis of Substituted 2-Pyridones via 6π-Electrocyclization of Dienyl Isocyanates
Cheng, Xiayun,Taylor, Alexandria P.,Zhu, Kaicheng
supporting information, p. 6403 - 6409 (2022/05/04)
A one-pot Curtius rearrangement of dienyl carboxylic acids followed by a 6π-electrocyclization process to form substituted 2-pyridone products has been developed. Dienyl isocyanates generated from aliphatic acids were more reactive than their aromatic counterparts. Additionally, substitution patterns of the carboxylic acids had an impact on the efficiency of the cyclization.