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249920-06-7

2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 249920-06-7 Structure

  • Basic information

    1. Product Name: 2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI)
    2. Synonyms: 2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI);(R)-1-(pyridin-2-yl)propan-1-amine
    3. CAS NO:249920-06-7
    4. Molecular Formula: C8H12N2
    5. Molecular Weight: 136.19
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 249920-06-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 214.1±15.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 0.998±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.02±0.39(Predicted)
    10. CAS DataBase Reference: 2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI)(249920-06-7)
    12. EPA Substance Registry System: 2-Pyridinemethanamine,alpha-ethyl-,(alphaR)-(9CI)(249920-06-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 249920-06-7(Hazardous Substances Data)

249920-06-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 249920-06-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,9,9,2 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 249920-06:
(8*2)+(7*4)+(6*9)+(5*9)+(4*2)+(3*0)+(2*0)+(1*6)=157
157 % 10 = 7
So 249920-06-7 is a valid CAS Registry Number.

249920-06-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R)-1-(2-Pyridinyl)-1-propanamine

1.2 Other means of identification

Product number -
Other names Cilastatinum [Latin]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:249920-06-7 SDS

249920-06-7Relevant articles and documents

ORGANIC COMPOUNDS

-

Page/Page column 39, (2010/03/02)

The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Synthesis and structure-activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists

Yu, Younong,Dwyer, Michael P.,Chao, Jianping,Aki, Cynthia,Chao, Jianhua,Purakkattle, Biju,Rindgen, Diane,Bond, Richard,Mayer-Ezel, Rosemary,Jakway, James,Qiu, Hongchen,Hipkin, R. William,Fossetta, James,Gonsiorek, Waldemar,Bian, Hong,Fan, Xuedong,Terminelli, Carol,Fine, Jay,Lundell, Daniel,Merritt, J. Robert,He, Zhenmin,Lai, Gaifa,Wu, Minglang,Taveras, Arthur

, p. 1318 - 1322 (2008/09/19)

Comprehensive SAR studies were undertaken in the 3,4-diaminocyclobut-3-ene-1,2-dione class of CXCR2/CXCR1 receptor antagonists to explore the role of the heterocycle on chemokine receptor binding affinities, functional activity, as well as oral exposure in rat. The nature of the heterocycle as well as the requisite substitution pattern around the heterocycle was shown to have a dramatic effect on the overall biological profile of this class of compounds. The furyl class, particularly the 4-halo adducts, was found to possess superior binding affinities for both the CXCR2 and CXCR1 receptors, functional activity, as well as oral exposure in rat versus other heterocyclic derivatives.

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