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1-Amino-1,2,4-triazole was used as a reactant in the synthesis of 1-[(5-nitrothenylidene)amino]azole derivatives for potential antichagasic drug development. While the resulting compounds demonstrated in vitro trypanocidal activity comparable to Nifurtimox, they were ineffective in eradicating Trypanosoma cruzi infections in vivo or preventing parasite survival in stored blood. The study highlights its role as a precursor but does not provide specific conclusions about 1-amino-1,2,4-triazole itself beyond its participation in the synthesis process.

24994-60-3

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24994-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 24994-60-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,9,9 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 24994-60:
(7*2)+(6*4)+(5*9)+(4*9)+(3*4)+(2*6)+(1*0)=143
143 % 10 = 3
So 24994-60-3 is a valid CAS Registry Number.
InChI:InChI=1/C2H4N4/c3-6-2-4-1-5-6/h1-2H,3H2

24994-60-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2,4-triazol-1-amine

1.2 Other means of identification

Product number -
Other names 1-AMINO-1,2,4-TRIAZOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24994-60-3 SDS

24994-60-3Upstream product

24994-60-3Relevant academic research and scientific papers

Triazolylated teritiary amine compound or salt thereof

-

, (2008/06/13)

A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomergaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl.

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