25022-23-5Relevant academic research and scientific papers
Method for the Direct Enantioselective Synthesis of Chiral Primary α-Amino Ketones by Catalytic α-Amination
Han, Yixin,Corey
supporting information, p. 283 - 286 (2019/01/10)
A useful catalytic enantioselective approach has been developed for the synthesis of chiral ketamine analogs using Rh(II)-catalyzed amination of triisopropylsilyl enol ethers to form α-amino ketones with O-(4-nitrophenyl)hydroxylamine as nitrogen donor in 81-91% ee.
Cu(II)-Mediated N-H and N-Alkyl Aryl Amination and Olefin Aziridination
Munnuri, Sailu,Anugu, Raghunath Reddy,Falck, John R.
supporting information, p. 1926 - 1929 (2019/03/11)
Cu(II)-mediated direct NH2 and NH alkyl aryl aminations and olefin aziridinations are described. These room-temperature, one-pot, environmentally friendly procedures replace costly Rh2 catalysts and, in some instances, display important differences with comparable Rh2- and Fe-supported reactions.
Synthese d'aziridines: Action d'organomagnesiens sur des iodures de N,N,N-trimethylhydrazonium
Arseniyadis, Simeon,Laurent, Andre,Mison, Pierre
, p. 246 - 254 (2007/10/02)
The reaction of Grignard reagents with N,N,N-trimethyl hydrazonium iodides provides a good method for the synthesis of secondary aziridines and specialy for aziridines 17a, b, 22, 24 and 25 which cannot be prepared by the Hoch-Campbell procedure (1) (reac
