250222-67-4

Upstream product

• 191163-58-3 1-(3-C-Allyl-3,5-di-O-benzyl-2-O-methylsulfonyl-β-D-ribofuranosyl)thymine 
• 250222-58-3 1-{3,5-Di-O-benzyl-3-C-[(2RS)-2,3-dihydroxypropyl]-β-D-arabinofuranosyl}thymine 
• 250222-57-2 1-[3,5-Di-O-benzyl-3-C-[(2RS)-2,3-dihydroxypropyl]-2-O-methylsulfonyl-β-D-ribofuranosyl]thymine 
• 250222-63-0 (1S,3R,5R,6R,8R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyldimethylsilyloxymethyl)-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane 
• 250222-60-7 1-{3,5-Di-O-benzyl-3-C-[(2S)-3-tert-butyldimethylsilyloxy-2-hydroxypropyl]-β-D-arabinofuranosyl}thymine 
• 1055041-78-5 Toluene-4-sulfonic acid (S)-2-[(2R,3S,4S,5R)-3-benzyloxy-2-benzyloxymethyl-4-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethyl ester 
• 199931-09-4 1-(3-C-Allyl-3,5-di-O-benzyl-β-D-arabinofuranosyl)thymine 
• 108-24-7 acetic anhydride 
• 250222-61-8 (1S,3R,5R,6R,8R)-5-Benzyloxy-6-benzyloxymethyl-3-hydroxymethyl-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane 

Downstream Products

• 250222-71-0 (1S,3R,5R,6R,8R)-3-Acetoxymethyl-6-(4,4'-dimethoxytrityloxomethyl)-5-hydroxy-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane 
• 250222-73-2 (1S,3R,5R,6R,8R)-3-Acetoxymethyl-5-[2-cyanoethoxy(diisopropylamino)phosphinoxy]-6-(4,4'-dimethoxytrityloxomethyl)-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane 

Relevant academic research and scientific papers

Oligonucleotide analogues containing (2″S)- And (2″R)-2′-O,3′-C-((2″-C-hydroxymethyl)ethylene)-linked bicyclic nucleoside monomers: F Synthesis, RNA-selective binding, and diastereoselective formation of a very stable homocomplex based on T : T base pairi

The 2′-O,3′-C-[(2″R)-2″-C-(acetoxymethyl)ethylene]- linkedand2′-O,3′-C-[(2″5)-2"-C-(acetoxymethyl)ethylene]- linked bicyclic thymine nucleosides 12R and 125 have been synthesized and transformed into the phosphoramidite derivatives 14R and 14S, respective