250236-00-1Relevant articles and documents
Methyllithium-promoted Wittig rearrangements of α-alkoxysilanes
Maleczka Jr., Robert E.,Geng, Feng
, p. 1115 - 1118 (2008/02/09)
(matrix presented) The Wittig rearrangements of α-alkoxysilanes, promoted by the action of methyllithium were studied. Depending on both the substrate and reaction conditions employed, [2,3]-, [1,2]-, or [1,4]-Wittig rearrangements can be realized. These rearrangements were shown to be initiated by either Si/Li exchange or deprotonation a to the silane. Furthermore the sigmatropic shifts can often be followed by other synthetically useful in situ chemical events.