25025-59-6 Usage
Chemical Properties
WHITE CRYSTALLINE POWDER
Purification Methods
It is a hygroscopic solid which can be recrystallised from ligroin/EtOH (1:1), dried and kept in a vacuum desiccator. Crystallisation from *C6H6/EtOH gives m 227o or from propan-1-ol the m is 213o. [Hansen Acta Chem Scand 11 537 1957, Heilbronn Acta Chem Scand 12 1481 1958, Beilstein 4 IV 1585.]
Check Digit Verification of cas no
The CAS Registry Mumber 25025-59-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,0,2 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25025-59:
(7*2)+(6*5)+(5*0)+(4*2)+(3*5)+(2*5)+(1*9)=86
86 % 10 = 6
So 25025-59-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H16NOS.BrH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
25025-59-6Relevant articles and documents
Conversion of cysteine into dehydroalanine enables access to synthetic histones bearing diverse post-translational modifications
Chalker, Justin M.,Lercher, Lukas,Rose, Nathan R.,Schofield, Christopher J.,Davis, Benjamin G.
supporting information; experimental part, p. 1835 - 1839 (2012/04/04)
Six for the price of one: From a single precursor, dehydroalanine, six distinct post-translational modifications can be site-selectively installed on histone proteins (see figure), including the first site-selective phosphorylation and glycosylation of histones. Direct observation of histone deacetylase activity on a full-length modified histone as well as its interactions with both chromatin reader and writer/eraser proteins are reported.