250277-53-3Relevant academic research and scientific papers
Total synthesis of vancomycin - Part 3: Synthesis of the aglycon
Nicolaou,Koumbis, Alexandros E.,Takayanagi, Masaru,Natarajan, Swaminathan,Jain, Nareshkumar F.,Bando, Toshikazu,Li, Hui,Hughes, Robert
, p. 2622 - 2647 (2007/10/03)
The total synthesis of the vancomycin aglycon (2, Figure 1) is described. Construction of the key intermediate, tricyclic triazene 3 a (Figure 2), was accomplished in the order C-O-D →AB/C-O-D →AB/C-O-D/D-O-E. The C-O-D ring system 18a (Scheme 2) was form
