25029-33-8 Usage
General Description
2-Deoxy-L-glucose is a chemical compound that is similar in structure to glucose, but it is missing a hydroxyl group at the 2-position on the sugar ring. 2-Deoxy-L-glucose is often used in scientific research and has been studied for its potential as a cancer treatment. It has been found to inhibit the growth of cancer cells by disrupting their glucose metabolism, effectively starving the cells of the energy they need to proliferate. In addition to its potential anticancer properties, 2-Deoxy-L-glucose has also been studied for its potential in treating neurodegenerative diseases, diabetes, and cardiovascular diseases. Its ability to interfere with glucose metabolism makes it a promising candidate for further research and potential therapeutic applications in the future.
Check Digit Verification of cas no
The CAS Registry Mumber 25029-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,0,2 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 25029-33:
(7*2)+(6*5)+(5*0)+(4*2)+(3*9)+(2*3)+(1*3)=88
88 % 10 = 8
So 25029-33-8 is a valid CAS Registry Number.
25029-33-8Relevant articles and documents
SILYL NITRONATES AND NITRILE OXIDES IN ORGANIC SYNTHESIS. A NOVEL ROUTE TO D,L-DEOXYSUGARS. USE OF ALUMINIUM OXIDE AS SOLID PHASE BASE FOR GENERATION OF NITRILE OXIDES FROM HYDROXIMIC ACID CHLORIDES
Torssell, K. B. G.,Hazell, A. C.,Hazell, R. G.
, p. 5569 - 5576 (2007/10/02)
Novel methodology is developed for a three step synthesis of deoxyaldoses and deoxyketoses. 1.Regioselective addition of silyl nitronate or nitrile oxide to a diene. 2.Stereospecific hydroxylation of the double bond. 3.Unmasking of the aldol moiety by catalytic reduction of the 2-isoxazoline.The syntheses of D.L-deoxyribose, D,L-oleose, D,L-digitoxose, D,L-2-deoxygalactose, 1,3-dideoxyfructose, 3-deoxyfructose etc. are described.Basic aluminium oxide is introduced as a solid phase base for the one step synthesis of 2-isoxazolines from aldoximes and olefins.An X-ray diffraction study of compound 13c verifies the stereochemical assignments.
