250592-95-1Relevant academic research and scientific papers
Design, synthesis and evaluation of phenethylaminoheterocycles as K v1.5 inhibitors
Johnson, James A.,Xu, Ningning,Jeon, Yoon,Finlay, Heather J.,Kover, Alexander,Conder, Mary L.,Sun, Huabin,Li, Danshi,Levesque, Paul,Hsueh, Mei-Mann,Harper, Timothy W.,Wexler, Ruth R.,Lloyd, John
, p. 3018 - 3022 (2014/06/24)
Phenethylaminoheterocycles have been prepared and assayed for inhibition of the Kv1.5 potassium ion channel as a potential approach to the treatment of atrial fibrillation. A diverse set of heterocycles were identified as potent Kv1.
Isoxazole carboxamide derivatives as ghrelin receptor modulators
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Page/Page column 12; 13, (2010/11/08)
The present invention is related to compounds of formula (I), or a therapeutically suitable salt or prodrug thereof, the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders regulated by ghrelin including anorexia, cancer cachexia, eating disorders, age-related decline in body composition, weight gain, obesity, and diabetes mellitus.
