250593-27-2Relevant academic research and scientific papers
Stereocontrolled total synthesis of (±)-catharanthine via radical-mediated indole formation
Reding, Matthew T.,Fukuyama, Tohru
, p. 973 - 976 (2008/02/09)
(matrix presented) A stereocontrolled total synthesis of (±)-catharanthine, 1, has been completed. The key step involves the radical-mediated cyclization of a highly functionalized intermediate to furnish the corresponding indole. The cyclization utilizes
