2506-20-9 Usage
General Description
L-Tetrahydropalmatine hydrochloride is a chemical compound that belongs to the class of tetrahydroprotoberberines. It has been used in traditional Chinese medicine for its potential therapeutic effects, particularly in the treatment of neurological and psychiatric disorders. L-Tetrahydropalmatine hydrochloride has been studied for its analgesic, anxiolytic, and sedative properties, and has shown promise in alleviating symptoms of drug addiction and withdrawal. It is believed to act on various neurotransmitter systems in the brain, including dopamine, serotonin, and norepinephrine, which may contribute to its therapeutic effects. Research on L-Tetrahydropalmatine hydrochloride is ongoing, and it is being investigated for its potential as a treatment for conditions such as anxiety, depression, and substance abuse disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 2506-20-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,0 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2506-20:
(6*2)+(5*5)+(4*0)+(3*6)+(2*2)+(1*0)=59
59 % 10 = 9
So 2506-20-9 is a valid CAS Registry Number.
2506-20-9Relevant articles and documents
Bioactive isoquinoline alkaloids from Corydalis saxicola
Huang, Qiao-Qin,Bi, Jun-Long,Sun, Qian-Yun,Yang, Fu-Mei,Wang, Yue-Hu,Tang, Gui-Hua,Zhao, Fu-Wei,Wang, Huan,Xu, Jin-Jin,Kennelly, Edward J.,Long, Chun-Lin,Yin, Ge-Fen
experimental part, p. 65 - 70 (2012/06/18)
Twelve isoquinoline alkaloids including two new nitro-containing tetrahydroprotoberberines, (-)-2,9-dihydroxyl-3,11-dimethoxy-1,10- dinitrotetrahydroprotoberberine (1) and (+)-4-nitroisoapocavidine (2), were isolated from the whole plant of Corydalis saxicola Bunting. The structures of the new compounds were established by spectroscopic analysis and chemical evidence. The inhibitory activity of these isolates against cholinesterase and canine parvovirus were evaluated. Compounds 1 and 1a, (+)-1-nitroapocavidine (5), berberine (8), palmatine (9), dehydrocavidine (10), and sanguinarine (11) showed potent inhibitory activity against acetylcholinesterase with IC 50 values of less than 10M, while only compound 1 possessed weak activity against canine parvovirus. Structure-activity studies demonstrated that the nitro substituents at ring A in the tetrahydroprotoberberines led to an increase in the anti-acetylcholinesterase activity.
