250613-76-4

Upstream product

• 250613-67-3 7-benzyloxy-3-butyl-4-oxo-oct-5-enoic acid ethyl ester 
• 109-72-8 n-butyllithium 

Relevant academic research and scientific papers

Silver(I)-catalyzed addition of zirconocenes to epoxy esters: A new entry to 1,4-dicarbonyl compounds and pyridazinones

(matrix presented) The Ag(I)-catalyzed tandem epoxy ester rearrangement-dioxycarbenium ion addition reaction with alkenyl zirconocenes provides 1,4-keto esters that can be further converted to substituted pyridazinones. The use of a fluorous tag in a cyclization-assisted cleavage strategy demonstrates the feasibility of extending this methodology to high-throughput organic synthesis.