250651-52-6Relevant articles and documents
Lithium bromide catalyzed solvent free method for synthesis of 2-substituted benzimidazoles and imidazopyridines
Dekhane, Deepak V.,Pawar, Shivaji S.,Gupta, Sunil V.,Shingare, Murlidhar S.,Thore, Shivaji N.
experimental part, p. 519 - 523 (2011/01/13)
The first successful lithium bromide mediated solvent free condensation of arylenediamine and esters to obtain 2-substituted benzimidazole and imidazopyridine in good to excellent yields is described.
Synthesis and some reactions of 2-acetylimidazo[4,5-b]pyridine. Antituberculotic activity of the obtained compounds
Bukowski,Janowiec,Zwolska-Kwiek,Andrzejczyk
, p. 651 - 654 (2007/10/03)
2-Acetylimidazo[4,5-b]pyridine was prepared and its reactions with some aromatic amines and sulfur (Willgerodt-Kindler reaction), some aromatic aldehydes, some carboxylic acid hydrazides as well as thiourea were investigated. New imidazo[4,5-b]pyridine derivatives with different substituents in 2-position (N-arylthioamides, imines, α β-unsaturated ketones, hydrazido-hydrazones and aminothiazole) were obtained. Most of the synthesized compounds were tested in vitro for their antituberculotic activity.