250660-54-9Relevant academic research and scientific papers
Studies on flavans. 1. Facile synthesis of (±)-7-hydxoxy-3′,4′-methylenedioxyflavan and (±)-4′-hydroxy-7-methoxyflavan by a BF3·Et2O-mediated pyran cyclization
Li,Yang,Li,Hou,Xue,Li
, p. 214 - 216 (2007/10/03)
A facile approach for the synthesis of flavans was developed by employing a BF3·Et2O-catalyzed pyran cyclization in an aprotic polar solvent as a key step, by which concise total syntheses of (±)-7-hydroxy-3′,4′-methylenedioxyflavan (1) and (±)-4′-hydroxy-7-methoxyflavan (2), two naturally occurring flavans, were achieved.
