250682-81-6Relevant articles and documents
2-polycyclic propynyl adenosine analogs having A2A agonist activity
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Page/Page column 25, (2008/06/13)
The invention provides compounds having the following general formula (I): wherein X, R1, R2, R7 and Z are as described herein.
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A2A receptor agonists
Sullivan, Gail W.,Rieger, Jayson M.,Michael Scheld,Macdonald, Timothy L.,Linden, Joel
, p. 1017 - 1026 (2007/10/03)
1. Novel 2-propynylcyclohexyl-5′-N-ehtylcarboxamidoadenosines, trans-substituted in the 4-position of the cyclohexyl ring, were evaluated in binding assays to the four subtypes of adenosine receptors (ARs). Two esters, 4-{(3-[6-amino-9-(5-ethylcarbamoyl-3