25069-29-8

Usage

Chemical structure

Consists of a 3-phenylprop-2-enoic acid backbone with a 4-diphenylamino substituent

Use in organic chemistry and pharmaceuticals

Due to potential biological activities and therapeutic properties

Studied effects

Anti-inflammatory, anti-cancer, and anti-diabetic

Potential as a building block

For the synthesis of novel drugs and bioactive compounds

Versatile and important molecule

In the development of new drugs and therapeutic agents

InChI:InChI=1/C21H17NO2/c23-21(24)16-13-17-11-14-20(15-12-17)22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-16H,(H,23,24)/b16-13+

Upstream product

• 141-82-2 malonic acid 
• 4181-05-9 4-(diphenylamino)benzaldehyde 

Relevant academic research and scientific papers

The self-aggregation of fluorophore-triphenylamine nanostructures with tunable luminescent properties: The effect of acidity and rare earth ions

A D-π-A type triphenylamine derivative 3-(4-(diphenylamino)phenyl) acrylic acid (abbreviated as L) is designed, synthesized and characterized by single crystal X-ray diffraction analysis. The self-aggregation of L nanostructures in different acidity aqueous solutions and/or under the guidance of rare earth (RE) ions is studied, along with the corresponding optical properties. In strong acidic conditions, L molecules self-assemble to form two dimensional nanostructures. While in neutral aqueous solutions, L tends to form nanorods. In the strong alkali environment, nanofibers were obtained. Moreover, in acidic conditions, the existence of Tm3+ induces the L molecules to self-aggregate into nanoplates. Flower-like six branched structures are observed when Yb3+ is used. The changed morphology leads to tunable linear optical properties.

Photocatalytic decarboxylative alkenylation of α-amino and α-hydroxy acid-derived redox active esters by NaI/PPh3 catalysis

Herein, we report the photocatalytic decarboxylative alkenylation reactions of N-(acyloxy)phthalimide derived from α-amino and α-hydroxy acids with 1,1-diarylethene, and with cinnamic acid derivatives through double decarboxylation, using sodium iodide and triphenylphosphine as redox catalysts. The reaction proceeds under mild irradiation conditions with visible blue light (440 nm or 456 nm) in an acetone solvent without recourse to transition-metal or organic dye based photoredox catalysts. The reaction proceeds via photoactivation of a transiently self-assembled chromophore from N-(acyloxy)phthalimide and NaI/PPh3. Solvation plays a crucial role in the reactivity.