250691-57-7 Usage
General Description
Salvisyrianone is a natural product found in Salvia of the section Sclarea, which has been isolated from the root extract of Salvia syriaca. It has a distinct diterpene skeleton and has been reported to exhibit various biological activities, including anti-malarial, cytotoxic, and anti-inflammatory properties. Studies have also shown that salvisyrianone possesses potent inhibitory effects on the enzyme glyoxalase-I and potentially exerts its anti-inflammatory activity through modulation of the NF-κB signaling pathway. As a result, salvisyrianone has garnered significant interest as a potential therapeutic agent for the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 250691-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,0,6,9 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 250691-57:
(8*2)+(7*5)+(6*0)+(5*6)+(4*9)+(3*1)+(2*5)+(1*7)=137
137 % 10 = 7
So 250691-57-7 is a valid CAS Registry Number.
250691-57-7Relevant articles and documents
Synthesis and antitumour activity of novel diterpenequinone salvicine and the analogs
Zhang, Jin-Sheng,Ding, Jian,Tang, Qin-Mei,Li, Mai,Zhao, Ming,Lu, Li-Juan,Chen, Ling-Ji,Yuan, Sheng-Tao
, p. 2731 - 2736 (1999)
A novel diterpenequinone named salvicine (4), structurally modified derivative of a natural product, and a series of the novel analogs have been prepared. Most of the analogs were found to be potently active against tumor cell lines in vitro. Further study on 4 in vivo demonstrated that it possessed a significant antineoplastic activity against murine S-180 Sarcoma and Lewis lung cancer, and human lung adenocarcinoma xenografts A-549 and LAX-83. The preclinical studies of 4 are now under way.