25074-12-8

Basic information

• Product Name: 3-Methyl-6-(4-methyl-3-pentenyl)benzofuran
• Synonyms: 3-Methyl-6-(4-methyl-3-pentenyl)benzofuran;Furoventalene
• CAS NO: 25074-12-8
• Molecular Formula: C15H18 O
• Molecular Weight: 214.3
• Mol File: 25074-12-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Methyl-6-(4-methyl-3-pentenyl)benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-6-(4-methyl-3-pentenyl)benzofuran(25074-12-8)
• EPA Substance Registry System: 3-Methyl-6-(4-methyl-3-pentenyl)benzofuran(25074-12-8)

Safety Data

• Hazardous Substances Data: 25074-12-8(Hazardous Substances Data)

Upstream product

• 78657-22-4 2,4,5,6,7aα-Hexahydro-7β-hydroxy-6β-(methoxycarbonyl)-3-methyl-6α-(4-methyl-3-pentenyl)-2-oxo-1-benzofuran 
• 78685-06-0 (6S,7S,7aR)-7-Hydroxy-3-methyl-6-(4-methyl-pent-3-enyl)-2-oxo-2,4,5,6,7,7a-hexahydro-benzofuran-6-carboxylic acid methyl ester 
• 78657-23-5 4,5,6,7-Tetrahydro-7β-hydroxy-6β-(methoxycarbonyl)-3-methyl-6α-(4-methyl-3-pentenyl)-1-benzofuran 
• 78657-24-6 (6S,7S)-7-Hydroxy-3-methyl-6-(4-methyl-pent-3-enyl)-4,5,6,7-tetrahydro-benzofuran-6-carboxylic acid methyl ester 
• 78657-25-7 (6R,7S)-7-Hydroxy-3-methyl-6-(4-methyl-pent-3-enyl)-4,5,6,7-tetrahydro-benzofuran-6-carboxylic acid 
• 78657-26-8 (6R,7R)-7-Hydroxy-3-methyl-6-(4-methyl-pent-3-enyl)-4,5,6,7-tetrahydro-benzofuran-6-carboxylic acid 
• 109950-48-3 4-[1-Hydroxy-1-methyl-2-(tetrahydro-pyran-2-yloxy)-ethyl]-3,5-dimethoxy-1-(4-methyl-pent-3-enyl)-cyclohexa-2,5-dienecarboxylic acid 
• 109950-50-7 3-Methyl-6-(4-methyl-pent-3-enyl)-4-oxo-4,5,6,7-tetrahydro-benzofuran-6-carboxylic acid methyl ester 
• 109950-51-8 3-Methyl-6-(4-methyl-pent-3-enyl)-6,7-dihydro-benzofuran-6-carboxylic acid methyl ester 
• 109950-46-1 3,5-Dimethoxy-1-(4-methyl-pent-3-enyl)-cyclohexa-2,5-dienecarboxylic acid 
• 43161-11-1 5-iodo-2-methylpent-2-ene 
• 78657-27-9 4,5-Dihydro-3-methyl-6-(4-methyl-3-pentenyl)-1-benzofuran 
• 30343-35-2 3-methyl-6-chlorobenzofuran 
• 2270-59-9 1-bromo-4-methylpent-3-ene 

Relevant articles and documents

New Route for Synthesis of Furan Derivatives from Protected α-Ketols and Ketones. A Total Synthesis of Furoventalene

Reaction of acetonyl tetrahydropyranyl ether (1) with ketones (2a-d) in the presence of lithium di-isopropylamide and zinc chloride produces the cross-aldol condensation products (3a-d), which are transformed into 3-methylfurans (4a-d), by treatment with

Regioselective Total Synthesis of Furoventalene, a Marine Natural Benzofuran, via the β-Vinylbutenolide Annulation

The framework of furoventalene (1) was regioselectively constructed from methyl 2-formyl-6-methyl-5-heptenoate (12) and 2,5-dihydro-3-methyl-4-vinyl-2-furanone (10) by consecutive 1,6 conjugate addition and aldol-type cyclization to lead to a diastereomeric mixture of bicyclic butenolides 13a and 13b.Both of the annulation products were transformed into 1 by a sequence of reactions: reduction, hydrolysis, dehydrative decarboxylation, and dehydrogenation via intermediates 14-16.The stereochemistry of the annulation products 13a and 13b is also discussed.