2510-74-9

Upstream product

• 26503-91-3 dithiocarbonic acid S-benzyl ester-O-(4-chloro-benzyl ester) 
• 908094-04-2 phenyldiazomethane 
• 118-75-2 chloranil 
• 72-54-8 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethane 
• 19277-54-4 p-chlorophenyldiazomethane 
• 51229-56-2 1-chloro-4-((phenylsulfonyl)methyl)benzene 
• 6966-45-6 4-chlorobenzylsulfonyl chloride 
• 104-88-1 4-chlorobenzaldehyde 
• 1530-39-8 (4-chlorobenzyl)triphenylphosphonium chloride 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 79183-98-5 1,2-dibromo-1,2-di-(p-chlorophenyl)-ethane 
• 7647-01-0 hydrogenchloride 
• 50-29-3 p,p'-DDT 
• 56960-97-5 1,2-bis(4-chlorophenyl)ethan-1-ol 

Downstream Products

• 62006-50-2 trans-1,2-bis-(p-chlorophenyl)ethane oxide 
• 79183-98-5 1,2-dibromo-1,2-di-(p-chlorophenyl)-ethane 
• 16740-47-9 meso-4.4'.α.α'-tetrachloro-bibenzyl 
• 16740-47-9 racem.-4.4'.α.α'-tetrachloro-bibenzyl 
• 5216-37-5 (E)-4,4'-dicyanostilbene 
• 116915-66-3 (1S,2S,2aR,7bR)-1,2-Bis-(4-chloro-phenyl)-1,2,2a,7b-tetrahydro-7a-aza-cyclobuta[e]indene 
• 38424-26-9 meso-p,p'-dichlorostilbene dibromide 
• 2510-74-9 (E)-1,2-di(4-chlorophenyl)ethene 
• 5216-35-3 1,2-bis(4-chlorophenyl)ethane 
• 62006-50-2 cis-4,4'-dichloro-α,α'-epoxy bibenzyl 
• 1138-47-2 trans-1,2-diphenylcyclopropane 
• 1081-75-0 1,3-diphenylpropane 
• 1138-48-3 cis-1,2-diphenylcyclopropane 
• 2001-61-8 rac-cis-1-(2-(4-chlorophenyl)cyclopropyl)benzene 

Relevant academic research and scientific papers

Energy-Transfer-Mediated Photocatalysis by a Bioinspired Organic Perylenephotosensitizer HiBRCP

Energy transfer plays a special role in photocatalysis by utilizing the potential energy of the excited state through indirect excitation, in which a photosensitizer determines the thermodynamic feasibility of the reaction. Bioinspired by the energy-transfer ability of natural product cercosporin, here we developed a green and highly efficient organic photosensitizer HiBRCP (hexaisobutyryl reduced cercosporin) through structural modification of cercosporin. After structural manipulation, its triplet energy was greatly improved, and then, it could markedly promote the efficient geometrical isomerization of alkenes from the E-isomer to the Z-isomer. Moreover, it was also effective for energy-transfer-mediated organometallic catalysis, which allowed realization of the cross-coupling of aryl bromides and carboxylic acids through efficient energy transfer from HiBRCP to nickel complexes. Thus, the study on the relationship between structural manipulation and their photophysical properties provided guidance for further modification of cercosporin, which could be applied to more meaningful and challenging energy-transfer reactions.

Efficient preparation method of symmetric diarylethene compound

The invention belongs to the technical field of fine chemicals and related chemistry, and provides an efficient preparation method of a symmetric diarylethene compound. The method comprises the following steps: with halomethyl-containing aromatic hydrocarbon and derivatives thereof as raw materials, conducting reacting at 100 DEG C for 12 hours in the presence of a catalyst, alkali, additives andan anhydrous organic solvent so as to obtain the corresponding diarylethene compound with symmetry. The method has the beneficial effects that no transition metal reaction exists, reaction conditionsare mild, operation is simple and convenient, the possibility of industrialization is realized, and the diarylethene compound is obtained at high yield; and the diarylethene compound synthesized by using the method can be further functionalized to obtain various compounds, and is applied to development and research of natural products, functional materials and fine chemicals.

HIGHLY SELECTIVE ELECTROCHEMICAL HYDROGENATION OF ALKYNES

Disclosed are electrochemical methods to prepare an alkane or an alkene, such as a cis- alkene, from an alkyne, or an alkane from an alkene. The method utilizes an electrochemical cell having a cathode and an anode and a reactor.

Photocatalyst-free visible light promoted: E → Z isomerization of alkenes

A simple and green method of visible light driven photocatalytic E to Z isomerization of alkenes has been developed. A variety of (Z)-alkenes can be prepared in the presence of visible light, without any additional photocatalyst. This protocol features photocatalyst-free conditions, which are mild, tolerant, and operationally simple, and is easy to implement.

A Bidentate Ru(II)-NC Complex as a Catalyst for Semihydrogenation of Alkynes to (E)-Alkenes with Ethanol

Four Ru(II)-NC complexes were tested as catalysts for semihydrogenation of internal alkynes to (E)-alkenes with ethanol, and the complex {(C5H4N)(C6H4)}RuCl(CO)(PPh3)2 (1a) showed the highest activity. The reactions proceeded well with 1 mol % catalyst loading and 0.1 equiv of t-BuONa at 110 °C for 1 h, and 32 alkenes were synthesized with excellent E:Z selectivity. This is the first ruthenium-catalyzed semihydrogenation of internal alkynes to (E)-alkenes using ethanol as the hydrogen donor.

Selenenate Anions (PhSeO?) as Organocatalyst: Synthesis of trans-Stilbenes and a PPV Derivative

The selenenate anion (RSeO?) is introduced as an active organocatalyst for the dehydrohalogen coupling of benzyl halides to form trans-stilbenes. It is shown that RSeO? is a more reactive catalyst than the previously reported sulfur analogues (sulfenate anion, RSO?) and selenolate anions (RSe?) in the aforementioned reaction. This catalytic system was also applied to the benzylic-chloromethyl-coupling polymerization (BCCP) of a bis-chloromethyl arene to form ppv (poly(p-phenylene vinylene))-type polymers with high yields, Mn (average molecular weight) up to 13,000 and ? (dispersity) of 1.15. (Figure presented.).

Diarylethene synthesis method without transition metal catalysis

The invention discloses a diarylethene synthesis method without transition metal catalysis. The method comprises the following steps: a cinnamic acid derivative and aryl trifluoroborate are subjectedto a decarboxylation coupling reaction in a solvent under the action of an oxidizing agent, postprocessing is performed after the reaction, and diarylethene is obtained. K2S2O8 is adopted to promote acatalytic system in the synthetic method, and a free radical coupling reaction can be performed directly under the condition that no ligand, transition metal or alkali is added. The method has widersubstrate range and higher yield; the method is simple to operate, reaction conditions are mild, and large-scale application is facilitated.

Preparation method of palladium catalyzed 1,2-trans diaryl alkene

The invention discloses a preparation method of palladium catalyzed 1,2-trans diaryl alkene. The method comprises the following steps that under the effects of catalysts, cocatalysts and alkali, arylacrylic acid and aromatic esters p-toluene sulfonate take decarboxylation coupling reaction in an organic solvent; after the reaction is finished, the 1,2-trans diaryl alkene is obtained through posttreatment. The method has the advantages that through C-O bond fracture, the operation is simple; a stable palladium catalyst with low cost is used; the substrate applicability is high; the harsh reaction conditions and the addition of strong alkali are not needed; the trans 1,2-diaryl alkene can be generated at high selectivity.

Copper-catalysed, diboron-mediated: Cis -dideuterated semihydrogenation of alkynes with heavy water

Methods to incorporate deuterium atoms into organic molecules are valuable for the pharmaceutical industry. Here, we found that diboron reagents can efficiently mediate the transfer of two D atoms from heavy water directly onto alkynes through copper-catalysed cis-selective semihydrogenation. Avoiding the use of costly and flammable D2 gas, this safe and practical process can proceed with excellent chemoselectivity and stereoselectivity. Utilizing the present method as the key step, the formal asymmetric total synthesis of d2-deuterium-labeled cis-combretastatin A4 is demonstrated. Mechanistic studies suggest that monoborylation of alkynes is the key step for this semihydrogenation process.

Palladium-catalyzed decarboxylative coupling of α,β-unsaturated carboxylic acids with aryl tosylates

We report a general method for selective cross-coupling of α,β-unsaturated carboxylic acids with aryl tosylates enabled by versatile Pd(II) complexes. This method features the general cross-coupling of ubiquitous α,β-unsaturated carboxylic acids by decarboxylation. The transformation is characterized by its operational simplicity, the use of inexpensive, air-stable Pd(II) catalysts, scalability and wide substrate scope. The reaction proceeds with high trans selectivity to furnish valuable (E)-1,2-diarylethenes.