25110-47-8Relevant academic research and scientific papers
Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
Zhou, Du-Chao,Lu, Yu-Ting,Mai, Yan-Wen,Zhang, Chen,Xia, Jie,Yao, Pei-Fen,Wang, Hong-Gen,Huang, Shi-Liang,Huang, Zhi-Shu
, (2019/08/06)
For the development of novel anticancer agents, we designed and synthesized a total of 37 perimidine o-quinone derivatives containing the o-quinone group at the A or B ring and different substituents (alkyl groups, aryl groups or heterocycles) at the C ri
A Cobalt Catalyst Permits the Direct Hydrogenative Synthesis of 1H-Perimidines from a Dinitroarene and an Aldehyde
Schwob, Tobias,Ade, Mirco,Kempe, Rhett
, p. 3013 - 3017 (2019/05/15)
A new sustainable catalytic reaction, the synthesis of 1H- perimidines from a dinitroarene and an aldehyde in the presence of H2, was achieved. An earth-abundant metal catalyst was developed to permit the efficient, highly chemoselective, and c
Synthesis of 2-aryl-1H-benzimidazoles and 2-aryl-1H-perimidines using arylidene Meldrum’s acid as a source of the aryl group and oxidant
Mehrabi, Hossein,Najafian-Ashrafi, Faezeh,Esfandiarpour, Zeinab,Ranjbar-Karimi, Reza
, p. 125 - 128 (2018/04/20)
Arylidene Meldrum’s acid is employed as a source of the aryl group and oxidant for the synthesis of 2-aryl-1H–benzimidazoles by a condensation reaction with 1,2-phenylenediamine in refluxing ethanol with good to high yields. Arylidene Meldrum’s acids were
An improved one-pot method for the preparation of 2-substituted 1H-perimidines
Maquestiau,Berte,Mayence,Vanden Eynde
, p. 2171 - 2180 (2007/10/02)
2-Substituted 1H-perimidines are readily prepared, in high yields, by refluxing a mixture of sodium pyrosulfite, an aldehyde, and 1,8-diaminonapthalene in aqueous ethanol or N,N-dimethylformamide. The method is of wide applicability except from
