251108-85-7Relevant academic research and scientific papers
Synthesis of Enantioenriched α,α-Dichloro- and α,α-Difluoro-β-Hydroxy Esters and Amides by Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation
Zheng, Long-Sheng,Phansavath, Phannarath,Ratovelomanana-Vidal, Virginie
, p. 5107 - 5111 (2018)
A mild and convenient approach was developed to prepare a series of α,α-dihalogeno β-hydroxy esters or amides by using commercially available Noyori's complex [RuCl(p-cymene)(R,R)-TsDPEN] as a catalyst (S/C = 100?200) in the asymmetric transfer hydrogenat
Rearrangement of N-allyl-α,α-dichloroamides, β- or γ-functionalized, to substituted analogues of the γ-aminobutyric acid (GABA)
Bellesia, Franco,Forti, Luca,Ghelfi, Franco,Ghirardini, Gianluca,Libertini, Emanuela,Pagnoni, Ugo M.,Pinetti, Adriano,Prochilo, Nicola
, p. 3739 - 3748 (2007/10/03)
The rearrange of γ-chloro, β-hydroxy or β-vinyl N-allyl-N-benzyl- α,α-dichlorocarboxyamides to γ-aminobutyric acid analogues is efficiently promoted by CuCl/N,N,N',N'-tetramethylethylendiamine. With the β-vinyl functionalization a tandem radical-radical r
