251115-21-6

Basic information

• Product Name: 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE
• Synonyms: 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE;4-Bromo-2-nitro-1-(trifluoromethyl)benzene, 5-Bromo-2-(trifluoromethyl)nitrobenzene;4-BroMo-2-nitro-1-(trifluoroMethyl)benzen
• CAS NO: 251115-21-6
• Molecular Formula: C₇H₃BrF₃NO₂
• Molecular Weight: 270.01
• Product Categories: Fluorine series
• Mol File: 251115-21-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 269℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.788
• Vapor Pressure: 0.0124mmHg at 25°C
• Refractive Index: 1.514
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE(251115-21-6)
• EPA Substance Registry System: 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE(251115-21-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 251115-21-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-nitro-1-(trifluoromethyl)benzene is an organic compound characterized by its bromine, nitro and trifluoromethyl substituents. The presence of these functional groups make it a useful reagent in organic synthesis. Organic synthesis is a special branch of chemical synthesis dealing with the construction of organic compounds via organic reactions. This chemical falls under the category of benzene and substituted derivatives. It is also identified by its unique CAS Registry Number, which is a numeric designation that can be used to identify any chemical substance. These numbers are assigned by the Chemical Abstracts Service, a division of the American Chemical Society.

InChI:InChI=1/C7H3BrF3NO2/c8-4-1-2-5(7(9,10)11)6(3-4)12(13)14/h1-3H

Upstream product

• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 3460-18-2 1,4-dibromo-2-nitrobenzene 

Downstream Products

• 1449581-09-2 7-trifluoromethyl-4-(4,4,5,5-tetramethyl-[1.3.2]dioxaborolan-2-yl)-1H-indole 
• 1360959-14-3 4-bromo-7-trifluoromethyl-1H-indole 
• 1350816-09-9 9-chloro-2-(5-(3-(dimethylamino)propyl)-2-(trifluoromethyl)phenylamino)-5H-benzo[b]pyrimido[4,5-d]azepine-6(7H)-thione 
• 1350816-41-9 9-chloro-2-{[5-[3-(dimethylamino)propyl]-2-(trifluoromethyl)phenyl]amino}-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-one 
• 1351438-85-1 di-tert-butyl ((Z)-{[5-[3-(dimethylamino)propyl]-2-(trifluoromethyl)phenyl]amino}methylylidene)biscarbamate 
• 1350816-40-8 5-[3-(dimethylamino)propyl]-2-(trifluoromethyl)aniline 
• 1350816-39-5 C₁₂H₁₁F₃N₂O₂ 
• 703-91-3 5-bromo-2-trifluoromethylphenylamine 

Relevant articles and documents

INHIBITORS OF JUN N-TERMINAL KINASE

The present disclosure provides inhibitors of c-Jun N-terminal kinases (JNK) having a structure according to the following formula (I): or a salt or solvate thereof, wherein ring A, Ca, Cb, Z, R5, W and Cy are defined herein. The disclosure further provides pharmaceutical compositions including the compounds of the present disclosure and methods of making and using the compounds and compositions of the present disclosure, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.

COMPOUNDS, COMPOSITIONS AND METHODS

Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.