25127-29-1 Usage
Description
Crebanine is an aporphine alkaloid, a type of organic compound derived from the aporphine group, which is a naturally occurring substance with a complex structure. It is characterized by its ability to sensitize TNF-α induced apoptosis and suppress human lung adenocarcinoma, making it a promising candidate for cancer research and treatment.
Uses
Used in Anticancer Applications:
Crebanine is used as an anticancer agent for its ability to sensitize TNF-α induced apoptosis and suppress human lung adenocarcinoma. This makes it a potential therapeutic agent in the fight against lung cancer, particularly adenocarcinoma, which is a common type of lung cancer.
Used in Pharmaceutical Research:
Crebanine is used as a research compound in the pharmaceutical industry for its potential to develop new cancer treatments. Its unique properties and interactions with biological systems make it a valuable tool for understanding the mechanisms of cancer cell growth and apoptosis, which can lead to the development of more effective therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 25127-29-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,1,2 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25127-29:
(7*2)+(6*5)+(5*1)+(4*2)+(3*7)+(2*2)+(1*9)=91
91 % 10 = 1
So 25127-29-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H21NO4/c1-21-7-6-11-8-16-20(25-10-24-16)18-12-4-5-15(22-2)19(23-3)13(12)9-14(21)17(11)18/h4-5,8,14H,6-7,9-10H2,1-3H3
25127-29-1Relevant articles and documents
THE ALKALOIDS OF STEPHANIA SASAKII: STRUCTURE OF FIVE NEW ALKALOIDS
Kunitomo, Jun-Ichi,Murakami, Yoshiko,Oshikata, Megumi,Shingu, Tetsuro,Akasu, Michinori,at al.
, p. 2735 - 2740 (2007/10/02)
Five new alkaloids, dehydrocrebanine, 4,5-dioxodehydrocrebanine, stesakine, dehydrostesakine, bisaknidinine and four known alkaloids, lirodenine, lanuginosine, 1-tetrahydropalmatine, d-isocorydine with a few alkaloids of unknown structure were newly isolated from Stephania sasakii.The structures of the new alkaloids were determined from spectral data and chemical evidence. - Key Word Index : Stephania sasakii; Menispermaceae; dehydrocrebanine; 4,5-dioxodehydrocrebanine; bisaknadinine; stesakine; dehydrostesakine.
