251317-83-6Relevant articles and documents
Synthesis and binding properties of photoactivable biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein
Teodori, Elisabetta,Ettori, Dominique,Garnier-Suillerot, Arlette,Gualtieri, Fulvio,Manetti, Dina,Novella Romanelli, Maria,Scapecchi, Serena
, p. 1873 - 1880 (1999)
The design and synthesis of two photoactivable biotin-labeled analogues of verapamil (6 and 7) is reported. Preliminary evaluation of the biological profile of 6 (EDP 137) and 7 (EDP 141) shows that they have comparable affinities to that of verapamil for