251318-99-7

Upstream product

• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 
• 123-73-9 crotonaldehyde 

Downstream Products

• 343262-81-7 (4S)-3-[(E)-(2S,3S)-3-(tert-butyldiphenylsilanoxy)-2-methyl-1-oxo-4-hexen-1-yl]-4-(phenylmethyl)-1,3-oxazolidin-2-one 
• 343262-80-6 (5S,10S,16S)-(6E,8Z,12E,14E)-3-benzenesulfonyl-16-(tert-butyldimethylsilanoxy)-16-[(E)-(2R,4S,5S,6R)-4-(tert-butyldimethylsilanoxy)-5-methyl-6-propenyltetrahydropyranyl]-5-triethylsilanoxy-8,10,12-trimethylhexadeca-6,8,12,14-tetraen-1-ol 
• 343263-00-3 (5S,10S,16S)-(6E,8Z,12E,14E)-3-benzenesulfonyl-16-(tert-butyldimethylsilanoxy)-16-[(E)-(2R,4S,5S,6R)-4-(tert-butyldimethylsilanoxy)-5-methyl-6-propenyltetrahydropyranyl]-5-triethylsilanoxy-8,10,12-trimethylhexadeca-6,8,12,14-tetraen-1-al 
• 343262-79-3 (2R,3S,4S,6R)-6-[(1S,7S,12S)-(2E,4E,8Z,10E)-14-benzenesulfonyl-1-(tert-butyldimethylsilanoxy)-12-triethylsilanoxy-5,7,9-trimethyltetradeca-2,4,8,10-tetraenyl]-4-(tert-butyldimethylsilanoxy)-3-methyl-2-E-propenyltetrahydropyran 
• 343262-78-2 2,2-dimethylpropionic acid (1S,6S,12S)-(2E,4Z,8E,10E)-1-(2-benzenesulfonylethyl)-12-(t-butyldimethylsilanoxy)-12-((E)-(2R,4S,5S,6R)-5-methyl-6-propenyl-4-(t-butyldimethylsilanoxy)-tetrahydropyran-2-yl)-4,6,8-trimethyldodeca-2,4,8,10-tetraenyl ester 
• 343263-02-5 (6S)-4-benzenesulfonyl-6-{(5S,11S)-(1E,3Z,7E,9E)-11-(tert-butyldimethylsilanoxy)-11-[(E)-(2R,4S,5S,6R)-4-(tert-butyldimethylsilanoxy)-5-methyl-6-propenyltetrahydropyran-2-yl]-3,5,7-trimethylundeca-1,3,7,9-teraenyl}-tetrahydropyran-2-one 
• 343263-01-4 (6S)-4-benzenesulfonyl-6-{(5S,11S)-(1E,3Z,7E,9E)-11-(tert-butyldimethylsilanoxy)-11-[(E)-(2R,4S,5S,6R)-4-(tert-butyldimethylsilanoxy)-5-methyl-6-propenyltetrahydropyran-2-yl]-3,5,7-trimethylundeca-1,3,7,9-teraenyl}-tetrahydropyran-2-ol 
• 343262-99-7 (1S,6S,12S)-(2E,4Z,8E,10E)-1-(2-benzenesulfonylethyl)-12-(t-butyldimethylsilanoxy)-12-((E)-(2R,4S,5S,6R)-5-methyl-6-propenyl-4-(t-butyldimethylsilanoxy)-tetrahydropyran-2-yl)-4,6,8-trimethyldodeca-2,4,8,10-tetraen-1-ol 
• 343262-88-4 2,2-dimethylpropionic acid (E)-(2S,3S,5S,6R,7R)-7-(tert-butyldiphenylsilanoxy)-2,3-epoxy-5-(4-methoxybenzyloxy)-6-methyldeca-8-enyl ester 

Relevant academic research and scientific papers

The synthesis of the C15-C24 segment of ratjadone

Ratjadone is an antifungal and highly cytotoxic polyketide from Sorangium cellulosum. The tetrahydropyran ring is supposed to result from an intramolecular opening of a C16-C17 epoxide. Herein we report the biomimetic synthesis of the C15-C24 segment of r