251361-24-7

Basic information

• Product Name: 7-hydroxy-8-methyl-2-oxo-2H-chromene-3-carboxylic acid benzyl ester
• CAS NO: 251361-24-7
• Molecular Weight: 310.306
• Mol File: 251361-24-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-hydroxy-8-methyl-2-oxo-2H-chromene-3-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-hydroxy-8-methyl-2-oxo-2H-chromene-3-carboxylic acid benzyl ester(251361-24-7)
• EPA Substance Registry System: 7-hydroxy-8-methyl-2-oxo-2H-chromene-3-carboxylic acid benzyl ester(251361-24-7)

Safety Data

• Hazardous Substances Data: 251361-24-7(Hazardous Substances Data)

Upstream product

• 608-25-3 2-methylbenzene-1,3-diol 
• 15014-25-2 malonic acid dibenzyl ester 
• 6248-20-0 2,4-dihydroxy-3-methylbenzaldehyde 

Relevant articles and documents

Synthesis and biological evaluation of coumarincarboxylic acids as inhibitors of gyrase B. L-rhamnose as an effective substitute for L-noviose

A series of novobiocin-like coumarincarboxylic acids has been prepared bearing the L-rhamnosyl moiety as the sugar portion of the molecule. The similar DNA gyrase inhibitory activity of the novel class of coumarins to that of novobiocin demonstrates that L-rhamnose can effectively replace L-novoise. Introduction of alkyl side-chains at C-5 of coumarin leads to improved in vitro antibacterial properties in the novel series.