25143-71-9Relevant academic research and scientific papers
Stereoselectivity in the Darzens condensation of substituted cyclohexanones with (-)-8-phenylmenthyl α-chloroacetate
Shinohara, Yoshihiro,Ohba, Yuko,Takagi, Ryukichi,Kojima, Satoshi,Ohkata, Katsuo
, p. 9 - 12 (2007/10/03)
The Darzens condensation of 4-monosubstituted and cis-3,5-dimethyl-cyclohexanones with (-)-8-phenylmenthyl α-chloroacetate proceeded to give mixtures of trans- and cis-glycidic esters with high enolate face selectivity (≥95% de). The presence of axial met
Synthetic applications of glycidic thiolesters. Regioselective reduction to 1,3-diols and 2,3-epoxy alcohols
Liu, Hsing-Jang,Luo, Weide
, p. 128 - 134 (2007/10/02)
Glycidic thiolesters were shown to undergo regioselective reduction with Raney nickel to give 1,3-diols.With sodium borohydride at room temperature and lithium aluminum hydride at -78 deg C, the reduction of glycidic thiolesters was found to proceed chemo
