251471-88-2Relevant academic research and scientific papers
Stereoselective synthesis of highly functionalized cyclobutenes. A facile route to electron-deficient 1,3-dienes
Yavari, Issa,Asghari, Sakineh
, p. 11853 - 11858 (1999)
Acetoacetanilide undergoes a smooth reaction with triphenylphosphine and dialkyl acetylenodicarboxylates to produce dialkyl 2-(acetoacetanilide-2-yl)- 3-(triphenylphosphoranilidene)-butandioates, which undergo intramolecular Wittig reaction to produce 2-methyl-3-(N-phenylcarbonyl)-1,4- dialkoxycarbonylcyclobutenes. These cyclobutene derivatives undergo electrocyclic ring-opening reactions in boiling toluene to produce highly electron-deficient 1,3-dienes.
