25152-20-9

Basic information

• Product Name: 5'-AMINO-5'-DEOXYTHYMIDINE
• Synonyms: 5'-AMINO-5'-DEOXYTHYMIDINE;5'-Amino-5'-deoxy-D-thymidine
• CAS NO: 25152-20-9
• Molecular Formula: C₁₀H₁₅N₃O₄
• Molecular Weight: 241.24
• Product Categories: Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
• Mol File: 25152-20-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.394 g/cm³
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 5'-AMINO-5'-DEOXYTHYMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-AMINO-5'-DEOXYTHYMIDINE(25152-20-9)
• EPA Substance Registry System: 5'-AMINO-5'-DEOXYTHYMIDINE(25152-20-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 25152-20-9(Hazardous Substances Data)

Usage

Uses

5''-Amino-5''-deoxythymidine (cas# 25152-20-9) is used in the methods and compositions for treatment of anti-angiogenic resistant cancer.

Downstream Products

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Relevant articles and documents

SYNTHESIS AND CHARACTERIZATION OF A CARBAMATE-LINKED OLIGONUCLEOSIDE

Reaction of 5'-O-dimethoxytritylthymidine with 1,1'-carbonyldiimidazole gave the 3'-O-carbonylimidazolide, which was condensed in high yield with 5'-amino-5'-deoxythymidine to produce a dinucleoside containing a 3'-O-5'-N-carbamoyl linkage.Four repetitions of carbonyl imidazolide formation and condensation produced a carbamate-linked hexamer.Hydrolytic and thermal denaturation studies did not indicate the presence of intramolecular base stacking.