251577-90-9Relevant articles and documents
Novel furanylarylene arylsulfonylindolesulfonamides: Synthesis and their antibacterial evaluation
Ramalingan, Chennan,Lee, In-Sook,Kwak, Young-Woo
experimental part, p. 591 - 596 (2009/12/27)
An array of furanylarylene arylsulfonylindolesulfonamides was synthesized through multi-step synthetic protocols involving bromination, stannylation, Stille cross coupling, reduction, arylsulfonylation, chlorosulfonylation, and condensation reactions. As
The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani
Stephens, Chad E.,Brun, Reto,Salem, Manar M.,Werbovetz, Karl A.,Tanious, Farial,Wilson, W. David,Boykin, David W.
, p. 2065 - 2069 (2007/10/03)
The in vitro activity of 20 dicationic molecules containing either diguanidino or reversed amidine cationic groups were evaluated versus Trypanosoma cruzi and Leishmania donovani. The most active compounds were in the reversed amidine series and six exhibited IC50 values of less than 1 μmol versus T. cruzi and five gave similar values versus L. donovani.