251901-57-2

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 251901-56-1 (2-phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-acetonitrile 
• 64307-20-6 (4E)-3-oxo-5-phenyl-4-pentenenitrile 
• 140399-50-4 3-((2E)-3-phenylprop-2-enoyl)-2H-chromen-2-one 
• 137-07-5 2-amino-benzenethiol 

Relevant academic research and scientific papers

Synthesis of benzo[b][1,4]thiazepines by the reaction of 3-aryl-1-(3-coumarinyl)propen-1-ones with 2-aminothiophenol [1]

(Chemical Equation Presented) 3-(2-Aryl-2,3-dihydro-benzo[b][1,4]thiazepin- 4-yl)chromen-2-ones (2a, e, f) and (Z)-3-(2,3-dihydro-2-arylbenzo[b][1,4] thiazepin-4(5H)-ylidene)chroman-2-ones (3a-f) have been synthesized by the reaction of 3-aryl-1-(3-coumarinyl)propen-1-ones (1a-f) with 2-aminothiophenol in a hot mixture of toluene and acetic acid. Structures of all new compounds and their complete 1H and 13C assignments were achieved applying different one- and two-dimensional nmr experiments in combination with various spectroscopic techniques.

Cinnamoylacetonitrile in heterocyclic synthesis, part 7 [1]. Simple synthesis of benzothiazepines, pyrones and oxazolopyridine

A facile synthesis of the entitled compounds is reported starting with cinnamonitrile.