251922-72-2

Upstream product

• 6281-32-9 4-quinolylmethanol 
• 111-19-3 sebacoyl chloride 
• 100-51-6 benzyl alcohol 
• 4363-93-3 quinoline-4-carboxaldehyde 
• 67852-87-3 monobenzyl sebacoyl chloride 

Downstream Products

• 67852-88-4 decanedioic acid monobenzyl ester 

Relevant academic research and scientific papers

4-Quinolylmethyl and 1-naphthylmethyl as benzyl-type protecting groups of carboxylic acids removable by homogeneous palladium-catalyzed hydrogenolysis

4-Quinolylmethyl (4-QUI) esters are reduced by palladium-catalyzed hydrogenolysis by formate anion. The reaction conditions are compatible with reducible substituents or functional groups as aromatic bromo, alkene, aldehyde, ketone, nitrile, ethyl and benzyl esters. An allyl ester is cleaved selectively in the presence of a 4-QUI ester. 1-Naphthylmethyl (1-NAP) esters of α-amino acids could be deprotected without any racemization by the same methodology. (C) 2000 Elsevier Science Ltd.

Arylmethyl esters as protecting groups for carboxylic, carbonic and carbamic acids: Deprotection via homogeneous palladium-catalyzed hydrogenolysis

4-Quinolylmethyl (4-QUI) esters of carboxylic acids and 1-naphthylmethyl (1-NAP) esters of carbonic and carbamic acids are reduced by palladium-catalyzed hydrogenolysis by formate anion. The reaction conditions are compatible with the presence of a benzyl ester and of an alkene double bond.