25198-95-2

Usage

Uses

5-Pyrimidinemethanamine (cas# 25198-95-2) is a compound useful in organic synthesis.

InChI:InChI=1/C5H7N3/c6-1-5-2-7-4-8-3-5/h2-4H,1,6H2

Upstream product

• 101346-02-5 5-pyrimidinylmethyl chloride 
• 10070-92-5 pyrimidine-5-carbaldehyde 
• 25193-95-7 5-(hydroxymethyl)pyrimidine 

Downstream Products

• 1439358-06-1 C₁₈H₁₆N₄O₃S 
• 1568916-86-8 C₂₁H₁₉N₅O 
• 1568916-46-0 C₁₅H₁₄N₂ 
• 1185165-49-4 C₁₈H₁₅N₃ 

Relevant academic research and scientific papers

CANCER TREATMENTS TARGETING CANCER STEM CELLS

Disclosed are compounds, methods, compositions, and kits that allow for treating cancer by, e.g., targeting cancer stem cells. In some embodiments, the cancer is colorectal cancer, gastric cancer, gastrointestinal stromal tumor, ovarian cancer, lung cancer, breast cancer, pancreatic cancer, prostate cancer, testicular cancer, or lymphoma. In some embodiments, the cancer is liver cancer, endometrial cancer, leukemia, or multiple myeloma. The compounds utilized in the disclosure are of Formula (0), (O'), and (I):

SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN

The present invention relates to compounds of formula (I) and to salts thereof, wherein R1, R2, and Q have any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of bromodomains. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various bromodomain-mediated disorders.