251980-66-2

Upstream product

• 2979-19-3 3,3-dimethylcyclohexanone 
• 68-12-2 N,N-dimethyl-formamide 
• 251980-67-3 2-bromo-4,4-dimethylcyclohex-1-ene-1-carbaldehyde 

Downstream Products

• 251980-64-0 (1R,4aR,4bR,7S,8aR,10aR)-1-[2-(2-bromo-4,4-dimethylcyclohex-1-enyl)ethyl]-7-tert-butyldimethylsiloxy-1,4b,8,8,10a-pentamethyl-1,4,4a,4b,5,6,7,8,8a,9,10,10a-dodecahydrophenanthren-2-yl trifluoromethanesulfonate 
• 251980-61-7 1,1,1-trifluoromethanesulfonic acid (1S,4aR,4bR,7S,8aR,10aR)-1-[2-(2-bromo-4,4-dimethylcyclohex-1-enyl)ethyl]-7-tert-butyldimethylsiloxy-1,4b,8,8,10a-pentamethyl-1,4,4a,4b,5,6,7,8,8a,9,10,10a-dodecahydrophenanthren-2-yl ester 
• 251980-63-9 (1R,4aR,4bR,7S,8aR,10aR)-1-[2-(2-bromo-4,4-dimethylcyclohex-1-enyl)ethyl]-7-tert-butyldimethylsiloxy-1,4b,8,8,10a-pentamethyldodecahydrophenanthren-2-one 
• 251980-60-6 (1S,4aR,4bR,7S,8aR,10aR)-1-[2-(2-bromo-4,4-dimethylcyclohex-1-enyl)ethyl]-7-tert-butyldimethylsiloxy-1,4b,8,8,10a-pentamethyldodecahydrophenanthren-2-one 
• 251980-59-3 (15S)-(3Z,7E,11E)-1-(2-bromo-4,4-dimethyl-1-cyclohexenyl)-4-tert-butyldimethylsiloxy-15,16-oxido-3,8,12,16-tetramethyl-3,7,11-pentadecatriene 
• 251980-58-2 2-bromo-1-(bromomethyl)-4,4-dimethylcyclohex-1-ene 
• 6040-30-8 aegiceradienol 

Relevant academic research and scientific papers

An exceptionally short and simple enantioselective total synthesis of pentacyclic triterpenes of the β-amyrin family

A new and very direct enantioselective total synthesis of members of the β-amyrin family of pentacyclic triterpenes has been developed starting with acylsilane 5, 2-propenyllithium, and cyclohexenylmethyl bromide 6, which were assembled to form tetraene 7

BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.