251982-49-7Relevant academic research and scientific papers
Enantioselective catalysis; 130: Optically active expanded ligands based on the trans-1,2-substituted cyclopentane skeleton
Brunner, Henri,Stefaniak, Stefan,Zabel, Manfred
, p. 1776 - 1784 (2007/10/03)
New expanded bisphosphane ligands with a chiral trans-1,2-substituted cyclopentane skeleton were prepared. Polyaldehydes were accessible by coupling optically active bisphosphane precursors with branched aryl bromides. Optically active expanded ligands were obtained by condensation of the aldehydes with chiral amines and amino alcohols. The optically active ligands were tested in several model reactions of enantioselective catalysis, including allylic alkylation, hydrogenation (adopted to the use of water), and hydrosilylation.
