252000-83-2

Upstream product

• 2140-79-6 2'-O-methyl adenosine 
• 76-83-5 trityl chloride 
• 28990-73-0 9-(2-O-methyl-5-O-trityl-β-D-ribofluranosyl)adenine 

Downstream Products

• 252001-19-7 3-{[5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-tetrahydro-furan-2-yl]-hydroxy-methyl}-6,6,8,8-tetraisopropyl-4-oxo-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene-1-carboxylic acid methyl ester 
• 252000-86-5 N⁶-benzoyl-9-(3-O-tert-butyldimethylsilyl-2-O-methyl-5-O-trityl-β-D-xylofuranosyl)adenine 
• 252000-88-7 N⁶-benzoyl-9-(3-O-tert-butyldimethylsilyl-2-O-methyl-β-D-xylofuranosyl)adenine 
• 252000-89-8 N⁶-benzoyl-9-(3-O-tert-butyldimethylsily-2-O-methyl-β-D-xylofuranos-5-urosyl)adenine 

Relevant academic research and scientific papers

The first synthesis of herbicidin B. stereoselective construction of the tricyclic undecose moiety by a conformational restriction strategy using steric repulsion between adjacent bulky silyl protecting groups on a pyranose ring

The first total synthesis of the nucleoside antibiotic herbicidin B (1b) was achieved, where a novel aldol-type C-glycosidation reaction promoted by samarium diiodide (SmI2) was used as a key step. Treatment of methyl 3,4-O-(1,1,3,3-tetraisopro