Welcome to LookChem.com Sign In|Join Free
  • or
CP-547632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF). It selectively targets VEGFR2 and bFGF over other related tyrosine kinases, such as EGFR and PDGF receptor β (PDGFRβ), and effectively inhibits VEGFR2 autophosphorylation induced by VEGF in various cell models. CP-547632 also demonstrates the ability to decrease angiogenesis induced by VEGF or bFGF and suppress tumor growth in athymic mice.

252003-65-9

Post Buying Request

252003-65-9 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

252003-65-9 Usage

Uses

Used in Pharmaceutical Industry:
CP-547632 is used as an anti-cancer agent for its ability to inhibit the growth of solid tumors by targeting VEGFR2 and bFGF, which play crucial roles in angiogenesis and tumor progression.
Used in Drug Development:
CP-547632 is used as a lead compound in the development of novel therapeutics for cancer treatment, particularly for targeting receptor tyrosine kinases involved in tumor growth and angiogenesis.
Used in Research Applications:
CP-547632 serves as a valuable research tool for studying the role of VEGFR2 and bFGF in various cellular processes, including cell proliferation, migration, and angiogenesis, as well as for investigating the mechanisms of action of potential anti-cancer drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 252003-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,0,0 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 252003-65:
(8*2)+(7*5)+(6*2)+(5*0)+(4*0)+(3*3)+(2*6)+(1*5)=89
89 % 10 = 9
So 252003-65-9 is a valid CAS Registry Number.

252003-65-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-(4-pyrrolidin-1-ylbutylcarbamoylamino)-1,2-thiazole-4-carboxamide

1.2 Other means of identification

Product number -
Other names 3-(4-Bromo-phenoxymethyl)-benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252003-65-9 SDS

252003-65-9Upstream product

252003-65-9Relevant academic research and scientific papers

PROCESSES FOR THE PREPARATION OF ISOTHIAZOLE DERIVATIVES

-

Page/Page column 34, (2008/06/13)

Processes and intermediates for the preparation of compounds of the Formula (1) and the pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, wherein R1, R2, and R3 have the definitions provided herei

Dosage forms and methods of treatment using VEGFR inhibitors

-

Page/Page column 6, (2008/06/13)

The invention provides dosage forms of a compound of formula 1: or pharmaceutically acceptable salts, solvates or prodrugs thereof. The invention further provides methods of treating hyperproliferative diseases, such as cancers, by administering the dosag

Isothiazole derivatives useful as anticancer agents

-

, (2008/06/13)

The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X1, R1, R2and R3are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods treating hyperproliferative disorders in mammals by administering the above compounds.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 252003-65-9