Basic information

Product Name: 3,4-DGE
Synonyms: 3,4-DGE;3,4-Dideoxyglucosone-3-ene min. 98%;(6R)-2-Hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one;(S)-2-hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one
CAS NO:252006-38-5
Molecular Formula: C6H8O4
Molecular Weight: 144.12532
EINECS: N/A
Product Categories: N/A
Mol File: 252006-38-5.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 381.5±42.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.401±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 10.58±0.40(Predicted)
CAS DataBase Reference: 3,4-DGE(CAS DataBase Reference)
NIST Chemistry Reference: 3,4-DGE(252006-38-5)
EPA Substance Registry System: 3,4-DGE(252006-38-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 252006-38-5(Hazardous Substances Data)

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Usage
SDS
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252006-38-5 Usage

Uses

Used in Pharmaceutical Applications:
3,4-DGE is used as a therapeutic agent for inducing apoptosis in human podocytes. This property makes it a potential candidate for the treatment of various diseases and conditions where the selective elimination of specific cell types is desired.
Used in Research Applications:
3,4-DGE is used as a research tool to study the mechanisms underlying apoptosis and the role of HSP27/HSPB1 expression in human podocytes. 3,4-DGE can help researchers gain a better understanding of the molecular pathways involved in cell death and survival, which may lead to the development of novel therapeutic strategies.
Used in Drug Development:
3,4-DGE is used as a lead compound in the development of new drugs targeting apoptosis. Its ability to decrease HSP27/HSPB1 expression and increase caspase-3 activation in mouse models suggests that it may have potential as a therapeutic agent for conditions where apoptosis is dysregulated, such as cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 252006-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,0,0 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 252006-38:
(8*2)+(7*5)+(6*2)+(5*0)+(4*0)+(3*6)+(2*3)+(1*8)=95
95 % 10 = 5
So 252006-38-5 is a valid CAS Registry Number.

252006-38-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name	(2R)-6-hydroxy-2-(hydroxymethyl)-2H-pyran-5-one

1.2 Other means of identification

Product number	-
Other names	2H-Pyran-3(6H)-one,2-hydroxy-6-(hydroxymethyl)-,(6R)

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252006-38-5 SDS

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