252191-22-3

Upstream product

• 252191-20-1 (3R,4R,5S)-4-Acetylamino-5-azido-3-((R)-1-ethyl-but-3-enyloxy)-cyclohex-1-enecarboxylic acid ethyl ester 
• 118629-75-7 (S)-2-hydroxypent-4-en-1-yl 4-methylbenzenesulfonate 
• 51795-28-9 (+)-(R)-5-hexen-3-ol 
• 252191-21-2 (3R,4R,5S)-4-Acetylamino-5-azido-3-((R)-1-oxiranylmethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 

Downstream Products

• 252191-17-6 (3R,4R,5S)-4-Acetylamino-5-amino-3-((R)-1-carboxymethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 
• 252191-18-7 (3R,4R,5S)-4-Acetylamino-5-amino-3-((R)-1-ethyl-3-hydroxy-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 
• 252191-23-4 (3R,4R,5S)-4-Acetylamino-5-azido-3-((R)-1-ethyl-3-oxo-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

Stereospecific synthesis of a GS 4104 metabolite: Determination of absolute stereochemistry and influenza neuraminidase inhibitory activity

The total synthesis for the determination of the absolute stereochemistry of a GS 4104 metabolite 3 is described. In addition, the influenza neuraminidase inhibitory activity of 3 and related intermediates are reported.