252289-06-8Relevant academic research and scientific papers
Natural product synthesis on polymeric supports - Synthesis and biological evaluation of an indolactam library
Meseguer, Benjamin,Alonso-Diaz, Daniel,Griebenow, Nils,Herget, Thomas,Waldmann, Herbert
, p. 2902 - 2906 (2007/10/03)
Potent activators of protein kinase C in fibroblasts: This property was determined for several indolactam V analogues (1) with a new cell-based assay system. This tumor-promoting indole alkaloid and analogues thereof can be synthesized efficiently on the solid phase. The key steps of the combinatorial approach are a regioselective amination of the indole ring and an enantioselective enzymatic reaction.
