252292-63-0Relevant academic research and scientific papers
Hydrogen-free reductive amination using iron pentacarbonyl as a reducing agent
Afanasyev, Oleg I.,Usanov, Dmitry L.,Chusov, Denis
supporting information, p. 10164 - 10166 (2017/12/26)
We developed solvent-free reductive amination without an external hydrogen source using iron pentacarbonyl as a reducing agent. Neither a catalyst nor any other additives were employed. Various types of substrates are suitable for the reaction, including
Reductive amination catalyzed by iridium complexes using carbon monoxide as a reducing agent
Moskovets, Alexey P.,Usanov, Dmitry L.,Afanasyev, Oleg I.,Fastovskiy, Vasilii A.,Molotkov, Alexander P.,Muratov, Karim M.,Denisov, Gleb L.,Zlotskii, Semen S.,Smol'Yakov, Alexander F.,Loginov, Dmitry A.,Chusov, Denis
supporting information, p. 6384 - 6387 (2017/08/10)
Development of novel, sustainable catalytic methodologies to provide access to amines represents a goal of fundamental importance. Herein we describe a systematic study for the construction of a variety of amines catalyzed by a well-defined homogeneous ir
Stereo- and regioselective gold-catalyzed hydroamination of internal alkynes with dialkylamines
Hesp, Kevin D.,Stradiotto, Mark
supporting information; experimental part, p. 18026 - 18029 (2011/03/16)
We report the use of a P,N-ligand to support a gold complex as a state-of-the-art precatalyst for the stereoselective hydroamination of internal aryl alkynes with dialkylamines to afford E-enamine products. Substrates featuring a diverse range of functional groups on both the amine (ether, sulfide, N-Boc amine, fluoro, nitrile, nitro, alcohol, N-heterocycles, amide, ester, and carboxylic acid) and alkyne (ether, N-heterocycles, N-phthalimide amines, and silyl ethers) are accommodated with synthetically useful regioselectivity.
