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(3S)-1-[1-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ETHYL]PYRROLIDIN-3-YLDIPHENYLACETONITRILE, also known as (S)-Darifenacin Nitrile, is a chemical compound that serves as an impurity in Darifenacin Hydrobromide (D193400), a medication used to treat urinary incontinence. (3S)-1-[1-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ETHYL]PYRROLIDIN-3-YLDIPHENYLACETONITRILE is characterized by its unique molecular structure, which includes a pyrrolidine ring and a diphenylacetonitrile group, along with a 2,3-dihydro-1-benzofuran-5-ylethyl moiety. Its specific stereochemistry at the 3S position is crucial for its properties and potential applications.

252317-48-9

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252317-48-9 Usage

Uses

Used in Pharmaceutical Industry:
(3S)-1-[1-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ETHYL]PYRROLIDIN-3-YLDIPHENYLACETONITRILE is used as an impurity in the manufacturing process of Darifenacin Hydrobromide, a medication for treating urinary incontinence. Its presence is significant as it can affect the purity and efficacy of the final drug product. (3S)-1-[1-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)ETHYL]PYRROLIDIN-3-YLDIPHENYLACETONITRILE works by blocking the M3 muscarinic acetylcholine receptor, which helps to reduce the symptoms of overactive bladder and incontinence.
In the pharmaceutical industry, maintaining the purity and quality of active pharmaceutical ingredients (APIs) is crucial. The presence of impurities such as (S)-Darifenacin Nitrile must be carefully controlled and monitored to ensure the safety and effectiveness of medications like Darifenacin Hydrobromide. This may involve the development of advanced purification techniques and quality control measures to minimize the presence of impurities and ensure that the final drug product meets regulatory standards and provides the desired therapeutic benefits to patients.

Check Digit Verification of cas no

The CAS Registry Mumber 252317-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,3,1 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 252317-48:
(8*2)+(7*5)+(6*2)+(5*3)+(4*1)+(3*7)+(2*4)+(1*8)=119
119 % 10 = 9
So 252317-48-9 is a valid CAS Registry Number.

252317-48-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name darifenacine hydrobromide

1.2 Other means of identification

Product number -
Other names (S)-2-{1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252317-48-9 SDS

252317-48-9Downstream Products

252317-48-9Relevant academic research and scientific papers

Method for obtaining 1,3-difunctionalized pyrrolidine derivatives

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Page/Page column 16-17, (2010/10/19)

The present invention relates to a method for obtaining 1,3-difunctionalized pyrrolidine derivatives, such as 3-(S)-(-)-(1-carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]pyrrolidine, commonly known as Darifenacin, as well as to the i

Stable hydrate of a muscarinic receptor antagonist

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, (2008/06/13)

A stable solid hydrate of a muscarinic receptor antagonist is useful in the treatment of irritable bowel syndrome, diverticular disease, oesophageal achalasia, chronic obstructive airways disease, over active bladder (including symptoms of incontinence, u

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