252377-18-7

Basic information

• Product Name: trans-(1R,2S,4S)-N-[(1'-diphenylphosphinyl-(3'R)-3'-(2-chlorophenyl)-(2'S)-2'-aziridinyl)carbonyl]bornane-10,2-sultam
• Synonyms: trans-(1R,2S,4S)-N-[(1'-diphenylphosphinyl-(3'R)-3'-(2-chlorophenyl)-(2'S)-2'-aziridinyl)carbonyl]bornane-10,2-sultam
• CAS NO: 252377-18-7
• Molecular Weight: 595.099
• Mol File: 252377-18-7.mol

Chemical Properties

• CAS DataBase Reference: trans-(1R,2S,4S)-N-[(1'-diphenylphosphinyl-(3'R)-3'-(2-chlorophenyl)-(2'S)-2'-aziridinyl)carbonyl]bornane-10,2-sultam(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(1R,2S,4S)-N-[(1'-diphenylphosphinyl-(3'R)-3'-(2-chlorophenyl)-(2'S)-2'-aziridinyl)carbonyl]bornane-10,2-sultam(252377-18-7)
• EPA Substance Registry System: trans-(1R,2S,4S)-N-[(1'-diphenylphosphinyl-(3'R)-3'-(2-chlorophenyl)-(2'S)-2'-aziridinyl)carbonyl]bornane-10,2-sultam(252377-18-7)

Safety Data

• Hazardous Substances Data: 252377-18-7(Hazardous Substances Data)

Upstream product

• 252377-07-4 N-(2-chlorobenzylidene)diphenylphosphinoylamide 
• 252577-46-1 (1R,2S,4S)-(+)-(N-bromoacetyl)bornane-10,2-sultam 

Relevant articles and documents

Asymmetric aziridine synthesis by aza-Darzens reaction of N-diphenylphosphinylimines with chiral enolates. Part 2: Inversion of diastereoselectivity

The aza-Darzens ('ADZ') reactions of N-diphenylphosphinyl ('N-Dpp') imines with chiral enolates derived from N-bromoacetyl 2S-2,10-camphorsultam proceed in generally good yield to give N-diphenylphosphinyl aziridinoyl sultams. However, the stereoselectivi

Inverted diastereoselectivity in asymmetric aziridine synthesis via aza-Darzens reaction of (2S)-N-bromoacyl camphorsultam

(formula presented) The aza-Darzens reaction of the chiral enolate derived from (2S)-bromoacetyl camphor sultam (1) with certain C-3-substituted N-diphenylphosphinyl imines gives mixtures of trans- and cis-aziridines. In some cases, only trans isomers are