2524-07-4Relevant academic research and scientific papers
Synthesis and cholinesterase inhibitory activity of n-phosphorylated / n-tiophosphorylated tacrine
Demkowicz, Sebastian,Dzierzbicka, Krystyna,Inkielewicz-Stepniak, Iwona,Kowalski, Szymon,Da?ko, Mateusz,Przyby?owska, Maja
, p. 947 - 957 (2020/08/19)
Background: Alzheimer’s disease (AD) is progressive and irreversible neurodegenera-tive disorder. Current pharmacotherapy is not able to stop progression of the disease and can only improve cognitive functions. Therefore, new drugs are being sought that w
An efficient synthesis of O,O- di propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime and its analogues: A potential marine toxin
Gupta, Arvind K.,Dubey,Parashar,Kaushik
scheme or table, p. 1892 - 1910 (2009/08/07)
An efficient method for the synthesis of Ptychodiscus brevis toxin O,O- di n-propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime (TG-1) and its analogues has been developed using thermally stable and recyclable silica gel and Na2SO4 as a condensing agent and water scavenger, respectively. The compounds were evaluated against fish Rasbora daniconius by determining the LC50 and LC90 values. The results of biological evaluation showed that these compounds have high degree of toxicity. Copyright Taylor & Francis Group, LLC.
Synthesis and Insecticidal Activity of N4-Aryl-N1-(O,O-dialkyl thiophosphoryl)Piperazines
Agarwal, Kamlesh C.
, p. 1170 - 1171 (2007/10/02)
Eleven new N4-aryl-N1-(O,O-dialkyl thiophosphoryl) piperazines have been synthesised as possible insecticides by the condensation of N-aryl piperazines with O,O-dialkyl chloro-tiophosphates and tested against Periplanata americana.
