25240-99-7

Upstream product

• 223600-50-8 1-(2-hydroxy-1-methyl-ethyl)-3-phenyl-urea 
• 62-53-3 aniline 
• 103-71-9 phenyl isocyanate 
• 21152-53-4 1-(1-hydroxypropan-2-yl)-3-phenylthiourea 
• 90875-47-1 N-(β-chloro-isopropyl)-N'-phenyl-urea 

Relevant academic research and scientific papers

A mild cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas to 2-phenylamino-2-oxazolines using TsCl/NaOH

An efficient synthesis of 2-phenylamino-2-oxazolines 3 via cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas 2 by a one-pot reaction using p-toluenesulfonyl chloride (TsCl) and NaOH in very good yields is described.

Investigation of the Mitsunobu reaction of N-(2-hydroxyethyl)-N'- phenyl-ureas

The Mitsunobu reaction of N-(2-hydroxyethyl)-ureas 1 using PPh3 and EtO2CN=NCO2Et led to the mixture of N- and O-alkylation products or a single isomer depending on the substrates.